Aciphex (Rabeprazole) is a Proton Pump Inhibitor (PPI) used to treat Gastroesophageal Reflux Disease (GERD), ulcers, erosive esophagitis, or zollinger-ellison syndrome. Aciphex works by blocking acid production in the stomach. It may be used in combination with antibiotics including amoxicillin or clarithromycin to treat certain types of ulcers. It may also be used to treat other conditions as determined by your doctor.
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Do not stop taking Aciphex even if you begin to feel better. Your symptoms may improve before your condition is fully treated.
Do not break, chew or split the tablets. Swallow them whole. They are specially formulated to release slowly in your body.
Aciphex decreases the amount of acid produced in your stomach.
Aciphex is used to treat ulcers, gastroesophageal reflux disease (GERD or heartburn), and other conditions involving excessive stomach acid production.
Aciphex may also be used for purposes other than those listed in this medication guide.
Talk to your doctor before taking Aciphex if you have liver disease. You may not be able to take Aciphex, or you may require a dosage adjustment or special monitoring during treatment if you have liver disease.
Aciphex is in the FDA pregnancy category B. This means that it is not expected to harm an unborn baby. Do not take Aciphex without first talking to your doctor if you are pregnant.
It is not known whether Aciphex passes into breast milk. Do not take Aciphex without first talking to your doctor if you are breast-feeding a baby.
Take Aciphex exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water.
Do not break, chew or split the tablets. Swallow them whole. They are specially formulated to release slowly in your body.
Do not stop taking Aciphex even if you begin to feel better. Your symptoms may improve before your condition is fully treated.
Store Aciphex at room temperature away from moisture and heat.
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless your doctor directs otherwise.
Seek emergency medical attention.
Symptoms of an Aciphex overdose are not known.
There are no restrictions on food, beverages, or activity while taking Aciphex, unless otherwise directed by your doctor.
Serious side effects from Aciphex are rare. If you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives) to Aciphex stop taking Aciphex and seek emergency medical attention.
Less serious side effects from Aciphex are also uncommon. Continue to take Aciphex and talk to your doctor if you experience
upset stomach or diarrhea;
headache;
insomnia or nervousness; or
a rash or itching.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Before taking Aciphex, tell your doctor if you are taking any of the following medicines:
ketoconazole (Nizoral),
ampicillin (Omnipen, Principen),
iron (Feosol, Mol-Iron, Fergon, Femiron, others),
digoxin (Lanoxin, Lanoxicaps), or
cyclosporine (Sandimmune, Neoral).
You may not be able to take Aciphex, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.
Drugs other than those listed here may also interact with Aciphex. Talk to your doctor and pharmacist
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