Champix (varenicline) is a medicine used to help with smoking cessation. The medication is available only to adults and with a prescription. It works best where smokers are committed to quit smoking and are receiving support. The smokers are required to set a date on which to stop smoking. The treatment typically takes 12 weeks. Champix (varenicline) works by reducing the pleasurable effects of smoking.
Smokers are usually addicted to nicotine (the chemical contained in tobacco). Nicotine binds the receptors and triggers the production of dopamine (a chemical messenger). This is what leads to the pleasurable effects. Varenicline binds these receptors thereby acting in two ways. First, it acts a partial agonist. It takes up the role of nicotine. This relieves the cravings. Second, the active ingredient acts as an antagonist where it works against nicotine to gradually reduce the pleasurable effects.
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Treatment with Champix (varenicline) works best on smokers who are highly motivated to stop smoking. Counseling is recommended before you start using the treatment. You will also need to pick a date on which you will stop smoking. Studies show it is possible to recover after stopping smoking 8 to 35 days after starting Champix treatment.
The treatment will take 12 weeks. The patient starts by taking a 0.5mg tablet, once a day for the first 3 days. The dose is then increased to two tablets of 0.5mg a day for the subsequent 4 days. The patient then takes two tablets of 1mg a day for the remaining 11 weeks.
If a patient does not successfully stop smoking after the 12 weeks, your doctor may recommend an additional treatment of 12 more weeks. The dose may be changed from time to time to achieve the best results.
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It is unknown if Champix (varenicline) can cause harm to an unborn baby. Animal studies have shown that this drug can increase the risk of reduced fetal weight, decreased fertility as well as increased auditory startle response.
Take the missed dose as soon as you remember but only if it is not almost time for the next dose. To avoid missing doses, make the point of taking the dose at the same time each day.
Store at room temperature and away from heat and moisture.
When using Champix (varenicline), a patient should be monitored for cardiovascular disease, seizure disorder and psychiatric disorders. Don’t miss any scheduled appointment with your doctor. You should also report new or worsening side effects.
Champix (varenicline) affects alcohol tolerance. The drug can also impede the metabolism of drugs like warfarin, theophylline and insulin. The drug has interactions with 7 tested drugs.
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